Background: The present study was undertaken with an objective to observe effectiveness of oral administration of cinnamon extract to hyperglycemic induced rats using alloxan. Male and female Wistar Rats were injected with alloxan to induce hyperglycemia.

Methods: This is an experimental study to determine whether cinnamon has an ability to combat hyperglycemic rats. Blood glucose was estimated by GOD-PAP method using diagnostic kit supplied by Agappe diagnostics, Maharashtra.

Results: The present experimental study provides further evidence that oral administration of Cinnamon extract for 21 days produced a significant decrease in the blood glucose level in the model of alloxan induced diabetes rats.

Conclusion: From this study, we can conclude that the oral
administration of Cinnamon extracts have beneficial effect on blood glucose levels. However further pharmacological and biochemical investigations will clearly elucidate the mechanism of action and helpful in projecting these plant extracts as a therapeutic target in diabetes research.

Background: Cataract is the leading cause of blindness worldwide, with surgery as a definitive therapy. Incisions may damage the underlying tissue, including loss of corneal sensibility. The purpose of this study was to determine differences in corneal sensibility decreased in patients after
phacoemulsification and SLIMCE.

Method: This study was a randomized clinical trial assessing
changes of corneal sensibility in immature senile cataract patients after phacoemulsification and SLIMCE at Sanglah and Indera Hospital Denpasar, Bali-Indonesia from March to August 2013. Surgeons and examiners are experienced ophthalmologists. Examiner did not know the initial data
subjects. Preoperative assessment of corneal sensibility on the first, eighth, and fifteenth days were assessed postoperative using Cochet-Bonnet aesthesiometer. Statistical analysis was performed by applying mean difference of two independent groups test with repeated measures of multiple
comparisons (ANOVA). Samples from each group were 17 eyes.

Results: There were significant differences in corneal sensibility on the first day postoperative (33.2 mm), day 8 (-21.5 mm), day 15 (-11.8 mm) in both groups. Decrease in corneal sensibility in both groups was significant (p = 0.001).
There was decreasing in corneal sensibility with SLIMCE technique in the first (21.8 mm) and eighth day (45.9 mm).

Conclusion: In phacoemulsification technique, corneal sensibility was also decreased in the first (31.8mm) and eighth day (50.6 mm) but returned to preoperative values on day 15 in both groups. Decrease in corneal sensibility during follow-up period is influenced by cataract surgery
technique (p = 0.017) and was higher in SLIMCE technique compared with phacoemulsification.

Background: Osteoporosis is a silent metabolic disease characterized by diminished bone mass and change in bone microstructure which cause increment of fracture risk. Until now, osteoporosis still becomes one of major health problems around the world. In Indonesia, the incidence of osteoporosis
is 25%. Previous study have shown the relation between osteoporosis and IL-6 gene polymorphism at
-572G>C and -174 G>C. There are some controversies about the correlation between these
polymorphism and osteoporosis because of different result between each study. Genotype G polymorphism at -572 G>C of IL-6 gene has been correlated with lower Bone mineral density (BMD) and Genotype G polymorphism at -174G>C of IL-6 gene has been correlated with higher BMD value.
In Indonesia, there are still no study about the association between IL-6 gene polymorphism and osteoporosis. In the future this IL-6 gene polymorphism could be used as a genetic marker for osteoporosis in postmenopausal woman. The objective of this study is to determine the difference of
genotype of -572G>C and -174G>C polymorphism of IL-6 gene and osteoporosis in Balinese postmenopausal women.

Method: This research design is a case control study. Sample was obtained at orthopedic outpatient clinic of Sanglah General Hospital, Bali-Indonesia from June 2012 until
November 2012. The diagnosis of osteoporosis is described as BMD value with T score ≤ -2.5 SD
using DEXA. All sample’s peripheral blood are taken to be isolated for DNA and analyzed for IL-6 gene polymorphism at -572G>C and -174G>C using Real Time PCR. Data obtained was analyzed with chi square test using SPSS.

Results: This research found 11 osteoporosis sample from total 52 with no difference sample characteristic between case and control (p > 0.05). Using Chi square test,
There was a significant differences between genotype -572 G>C; IL-6 gene polymorphism in Balinese postmenopausal woman with osteoporosis and in Balinese postmenopausal woman without osteoporosis (c2 = 41.85 and p = 0.001) and no significant differences between genotype -174
G>C;IL-6 polymorphism in Balinese postmenopausal woman with osteoporosis and in Balinese postmenopausal woman without osteoporosis(c2 = 0.283 and p = 0.518). This study discovered significant differences between genotype -572 G>C; IL-6 gene polymorphism in Balinese postmenopausal woman with osteoporosis and in Balinese postmenopausal woman without osteoporosis.

Conclusion: We concluded that ethnic genetic profile variations affect the role of IL-6 gene polymorphism. In the future, this IL-6 gene polymorphism could be used as risk factor for
osteoporosis in Balinese premenopausal woman

Background: Bilateral paramedian thalamic and midbrain infarct is rare and present with varying symptoms. The occlusion of a rare arterial variant called the artery of Percheron results in bilateral thalamic infarcts, with or without midbrain involvement. To this date, the diagnosis of ischemic
infarction due to occlusion of the artery of Percheronhas was uncommon.

Case: We reports a 50 yearold man with acute ischemic infarcts of both paramedian thalami and midbrain, presenting with complete ophthalmoplegia, arreactive mydriasis pupils, and altered mental status (somnolent and
fluctuating hypersomnia).

Conclusions: Based on clinical and neuroimaging findings, we concluded this case as acute ischemic infarctions due to occlusion of the artery of Percheron.

Background: Infantile capillary hemangioma or benign hemangio-endotelioma or strawberry nevus is a most common benign vascular tumor in children. This study aims to report management two cases of eyelid capillary hemangioma with intralesional injection of triamcinolone acetonide (TA).

Methods: Case report. First case is 11th months old baby, girl, with mass on right superior eyelid since 5th month old that getting bigger. Mass are soft, blue to purple colored, with size of 30 x 30 x 20 mm, obvious border, refined surface, fixated to beneath structure, and there were dilated blood vessels
visible from anterior surface. Second case is 1st month old baby with mass on left superior eyelid since a week after birth. On examination found soft mass with blue violet colour, size 30x30x5mm, smooth surface, fixated, dilated blood vessels at skin surface. There were multiple bright red marks with
variated size such as 2x3x1mm, 2x2 x1mm, 3x2x1mm at eyelid skin surface. Both cases were given timol 0.5% for two months, but mass were getting bigger until closing visual axis. On both cases there were mechanical ptosis that close visual axis. Closing of visual axis causes deprivational amblyopia,
so need intervention to reduces deprivation with intralesion TA injection at dose 3 mg/kg body weight.

Results: After TA intralesional injection, tumor size reduced on both cases so visual axis is opened, without side effect. Conclusion: triamcinolone acetonide intralesional injection on capillary hemangioma cases reduces tumor size on relatively short time, in the hope to maximally reduce deprivation amblyopia at visual development age.

Conclusion: triamcinolone acetonide intralesional injection on capillary hemangioma cases reduces tumor size on relatively short time, in the hope to maximally reduce
deprivation amblyopia at visual development age.