Skip to main content Skip to main navigation menu Skip to site footer

Effectiveness of milk kefir administration with the addition of sorghum flour against total cholesterol levels, and blood glucose levels in obesity-induced mice

Abstract

Introduction: Someone who is overweight has the potential to experience complications from various diseases which become a heavy economic burden for the community. Dietary modification is considered as one of the strategies to prevent and handling obesity. It can be done by adjust the type, amount, frequency, processing methods, and schedule. Maintenance of intestinal microflora can be done by regulating food intake by consuming foods or drinks that have physiological functions for health. Synbiotics can control the number of good micro-flora in the digestive tract, thus providing health and therapeutic benefits. The aim of this study was to see the effectiveness of milk kefir plus sorghum flour on maintain the cholesterol and blood glucose levels of mice that have been fed a high-fat diet or induced obesity.

Methods: This type of research design is true experimental in vivo using a randomized controlled pre-test-post-test control group design. Based on the test results using one way ANOVA statistical test which can be seen, it can be concluded that there are differences in blood glucose levels in the treatment group using the COD-PAP method with a p-value of 0,031.

Results: According to ANOVA test, there are differences in total cholesterol levels in the treatment group using the CHOD-PAP method with a p-value of 0,000.

Conclusion: There are differences in blood glucose and total cholesterol levels in mice fed kefir milk with the addition of sorghum flour.

References

  1. Cao SY. Dietary Plants, Gut Microbiota, and Obesity : Effect and Mechanisms. Trends Food Sci Technol. 2019;92:192–204.
  2. Organization WH. Obesity. who.int. 2016.
  3. M A. Hubungan Pola Makan Dan Tingkat Pengetahuan Dengan Kadar Asam Urat Dalam Darah Pada Penderita Gout Artritis Di Puskesmas Ranotana Weru. e-journal Keperawatan (e-Kp). 2019;7(1):1–8.
  4. E S. Pengaruh Konsentrasi Tepung Sorgum (Sorghum bicolor L. Moench) Terhadap Beberapa Karakteristik Minuman Sinbiotik. Asian J Environ Hist Herit. 2017;1(2):1–11.
  5. Khuswatun KS, Susanti S, Legowo AM. Karakteristik Es Krim Kefir Puree Buah Naga Merah Sebagai Pangan Fungsional Antiobesitas. J Food Technol Nutr. 2020;19(2):53–62.
  6. Saturti TIA. Inflammation in obesity: a review. Bali Med J. 2022;11(3):1935–8.
  7. Nogay NH. Kefir Beverage And Its Effect On Health: Milk-Based Beverage. Woodhead Publishing; 2019. 273–296 p.
  8. Suarni, Subagio H. Prospek pengembangan jagung dan sorgum sebagai sumber pangan fungsional. J Penelit dan Pengemb Pertan. 2013;32(3):47–55.
  9. MP S-O, ER F, PJH J. Consumption Of Fermented And Nonfermented Dairy Products: Effects On Cholesterol Concentrations And Metabolism. Am J Clin Nutr. 2000;71:674–81.

How to Cite

Kardina, R. N., Setiarsih, D., Santoso, A. P. R., Raharjeng, S. H., Putri, P. H. ., & Lestari, I. D. (2023). Effectiveness of milk kefir administration with the addition of sorghum flour against total cholesterol levels, and blood glucose levels in obesity-induced mice. Bali Medical Journal, 12(3), 3287–3289. https://doi.org/10.15562/bmj.v12i3.4463

HTML
0

Total
0

Share

Search Panel

Rizki Nurmalya Kardina
Google Scholar
Pubmed
BMJ Journal


Dini Setiarsih
Google Scholar
Pubmed
BMJ Journal


Andreas Putro Ragil Santoso
Google Scholar
Pubmed
BMJ Journal


Sa’bania Hari Raharjeng
Google Scholar
Pubmed
BMJ Journal


Pratiwi Hariyani Putri
Google Scholar
Pubmed
BMJ Journal


Indri Dwi Lestari
Google Scholar
Pubmed
BMJ Journal