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Factors attributed to depressive symptoms in women coping with infertility during the pandemic of COVID-19

  • Mila Maidarti ,
  • Emily Bailie ,
  • Aprilia Siregar ,
  • Prini Diandara Garinasih ,
  • Vita Silvana ,
  • Achmad Kemal Harzif ,
  • Gita Pratama ,
  • Kanadi Sumapraja ,
  • R Muharam ,
  • Andon Hestiantoro ,
  • Budi Wiweko ,

Abstract

Link of Video Abstract: https://youtu.be/2L4njgfd3SE

 

Background: The dissemination of coronavirus disease (COVID-19) has led to delayed infertility treatment and fear of contracting the virus which can affect the mental status of women with infertility. This research aimed to investigate whether fear, depression, perceptions, and knowledge related to COVID-19 affected infertility patients in seeking treatment and analyzed factors associated with depression during COVID-19 pandemic.

Method: This is a cross-sectional study utilizing an electronic survey distributed to infertility patients attending fertility services between May and July 2021. The primary outcomes were demographic characteristics, clinical parameters of infertility, depressive symptoms based on the Patient Health Questionnaire-9 (PHQ-9) score, and fear of COVID-19 scale (FCV-1 and FCV-2).

Results: A total of 533 patients were included. The fear of infertility treatment suspension due to COVID-19 was perceived by 34.1% of patients. The mean Patient Health Questionnaire-9 (PHQ-9) score was 4.55 ± 4.248, with mild depression occurring in 33.4% of patients. Low income, delayed treatment, and fear of COVID-19 scale (FCV-1) score together could significantly predict depression status. Despite the pandemic, 94.7% of patients decided to continue the treatment.

Conclusion: The COVID-19 pandemic has given rise to stressors that may aggravate the psychological condition of women with infertility. However, the enthusiasm to continue the treatment remains undisturbed. It is imperative to offer emotional support and address the consequences of COVID-19 infection in women with infertility during the pandemic era.

References

  1. American Society for Reproductive Medicine. Patient Management and Clinical Recommendations During the Coronavirus (COVID-19) Pandemic 2020 [updated 17 March 2020. 8]. Available from: https://www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/covid-19/covidtaskforce.pdf.
  2. European Society of Human Reproduction and Embryology. Assisted reproduction and COVID-19: A statement from ESHRE for phase 1 - Guidance on fertility services during pandemic 2020 [cited 2022 December 14]. Available from: https://www.eshre.eu/Europe/Position-statements/COVID19.
  3. Smith A, Gromski PS, Rashid KA, Tilling K, Lawlor DA, Nelson SM. Population implications of cessation of IVF during the COVID-19 pandemic. Reprod Biomed Online. 2020;41:428-430.
  4. Romanski PA, Bortoletto P, Rosenwaks Z, Schattman GL. Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve. Hum Reprod. 2020;35:1630-1636.
  5. Hill E, Baird M, Seetahul S. Indonesia and COVID-19 Impact on the private sector [internet]. UN Women; 2020 [28]. Available from: https://investinginwomen.asia/wp-content/uploads/2020/08/IW_UNW-Indonesia-report_Final.pdf.
  6. Wiweko B, Anggraheni U, Elvira SD, Lubis HP. Distribution of stress level among infertility patients. Middle East Fertil Soc J. 2017;22:145-148.
  7. Dida S, Hadisiwi P, Setianti Y. Information needs of Indonesian infertile patients about cross-border reproductive care. Int J Media Commun Res. 2021;2:37-50.
  8. Marom Haham L, Youngster M, Kuperman Shani A, Yee S, Ben-Kimhy R, Medina-Artom TR, et al. Suspension of fertility treatment during the COVID-19 pandemic: views, emotional reactions and psychological distress among women undergoing fertility treatment. Reprod Biomed Online. 2021;42:849-858.
  9. Ahorsu DK, Lin CY, Imani V, Saffari M, Griffiths MD, Pakpour AH. The Fear of COVID-19 Scale: Development and Initial Validation. Int J Ment Health Addict. 2022;20(3):1537-1545.
  10. Tokgoz VY, Kaya Y, Tekin AB. The level of anxiety in infertile women whose ART cycles are postponed due to the COVID-19 outbreak. J Psychosom Obstet Gynaecol. 2020:1-8.
  11. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606-613.
  12. Noorbala AA, Ramazanzadeh F, Malekafzali H, Abedinia N, Forooshani AR, Shariat M, et al. Effects of a psychological intervention on depression in infertile couples. Int J Gynaecol Obstet. 2008;101:248-252.
  13. Maroufizadeh S, Karimi E, Vesali S, Samani RO. Anxiety and depression after failure of assisted reproductive treatment among patients experiencing infertility. Int J Gynaecol Obstet. 2015;130:253-256.
  14. Guo Q, Zheng Y, Shi J, Wang J, Li G, Li C, et al. Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: A mixed-method study. Brain Behav Immun. 2020;88:17-27.
  15. Codagnone C, Bogliacino F, Gomez C, Charris R, Montealegre F, Liva G, et al. Assessing concerns for the economic consequence of the COVID-19 response and mental health problems associated with economic vulnerability and negative economic shock in Italy, Spain, and the United Kingdom. PLoS One. 2020;15:e0240876.
  16. Schweiger U, Schweiger JU, Schweiger JI. Mental disorders and female infertility. Arch Psychol. 2018;2:14.
  17. Barra F, La Rosa VL, Vitale SG, Commodari E, Altieri M, Scala C, et al. Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study. J Psychosom Obstet Gynaecol. 2022;43:145-152.
  18. Veiga A, Gianaroli L, Ory S, Horton M, Feinberg E, Penzias A. Assisted reproduction and COVID-19: A joint statement of ASRM, ESHRE and IFFS. Fertil Steril. 2020;114:484-485.
  19. Gordon JL, Balsom AA. The psychological impact of fertility treatment suspensions during the COVID-19 pandemic. PLoS One. 2020;15:e0239253.
  20. Broekmans FJ, Soules MR, Fauser BC. Ovarian aging: mechanisms and clinical consequences. Endocr Rev. 2009;30:465-493.
  21. Gupta M, Jaiswal P, Bansiwal R, Sethi A, Vanamail P, Kachhawa G, et al. Anxieties and apprehensions among women waiting for fertility treatments during the COVID-19 pandemic. Int J Gynaecol Obstet. 2021;152:441-443.
  22. Esposito V, Rania E, Lico D, Pedri S, Fiorenza A, Strati MF, et al. Influence of COVID-19 pandemic on the psychological status of infertile couples. Eur J Obstet Gynecol Reprod Biol. 2020;253:148-153.
  23. Doshi D, Karunakar P, Sukhabogi JR, Prasanna JS, Mahajan SV. Assessing Coronavirus Fear in Indian Population Using the Fear of COVID-19 Scale. Int J Ment Health Addict. 2021;19:2383-2391.
  24. Asai K, Wakashima K, Toda S, Koiwa K. Fear of novel coronavirus disease (COVID-19) among pregnant and infertile women in Japan. J Affect Disord Rep. 2021;4:100104.
  25. Lawson AK, McQueen DB, Swanson AC, Confino R, Feinberg EC, Pavone ME. Psychological distress and postponed fertility care during the COVID-19 pandemic. J Assist Reprod Genet. 2021;38:333-341.

How to Cite

Maidarti, M., Bailie, E., Siregar, A., Garinasih, P. D., Silvana, V., Harzif, A. K., Pratama, G., Sumapraja, K., Muharam, R., Hestiantoro, A., & Wiweko, B. (2023). Factors attributed to depressive symptoms in women coping with infertility during the pandemic of COVID-19. Bali Medical Journal, 12(2), 1247–1254. https://doi.org/10.15562/bmj.v12i2.4214

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