Skip to main content Skip to main navigation menu Skip to site footer

Relations between the incidence of endometriosis and type 1 epithelial ovarian cancer at M Djamil Central Hospital of Padang Indonesia

  • Syamel Muhammad ,
  • Ghina Muthmainnah ,


Introduction: The incidence of ovarian cancer is high and continues to increase yearly, especially in Padang. About 90% of them are the type of epithelial ovarian cancer. One of the predisposing factors of this cancer is endometriosis. Endometriosis has the same characteristics as malignant tumors, including the ability to invade other organs. It is known that endometriosis occurs in 7% -15% of women of childbearing age and has a variety of symptoms, making diagnosis difficult. This study aims to determine the relationship between the incidence of endometriosis and epithelial ovarian cancer in type 1 in Dr.M.Djamil Hospital Padang from 2017 to 2018.

Methods: This study is a cross-sectional analytic study. Subjects were obtained using a total sampling of ovarian cancer patients who went to the Obstetrics and Gynecology Dr. M.Djamil Hospital Padang from January 2017 - December 2018.

Results: The retrospective study used the data of epithelial ovarian cancer patients diagnosed at the Obstetrics and Gynecology Dr. M.Djamil Hospital Padang. The incidence of endometriosis was obtained at 8.3%, and the highest type of epithelial ovarian cancer is epithelial ovarian cancer type 1 (70.7%). The incidence of endometriosis had significantly increased in patients with ovarian cancer in type 1 with a significance value of 0,010.

Conclusion: The incidence of endometriosis was significantly associated with epithelial ovarian cancer type 1 because of p<0.05. Health agencies need extraordinary attention to prevent epithelial ovarian cancer endometriosis changes into type 1.


  1. Sevilla In, Linde FM, Sánchez M del PM, et al. Prognostic importance of endometriosis with architectural atypical hyperplasia versus cytologic atypia in endometriosis-associated ovarian cancer. J Gynecol Oncol. 2019; 30 (4): 1-12. DOI: 10.3802/jgo.2019.30.e63
  2. BM Reid, JB Permuth, Sellers TA. Epidemiology of ovarian cancer: a review Pathologic classification of OC. Cancer Biology and Medicine. 2017;14(1):9-32. DOI: 10.20892/j.issn.2095-3941.2016.0084
  3. Ligament B. Special Section: Ovarian cancer. Am Cancer Soc. 2018;45(2):28-43.
  4. Torre LA, Trabert B, DeSantis CE, et al. Ovarian Cancer statistics, 2018. CA Cancer J Clin. 2018; 68 (4): 284-96. DOI: 10.3322/caac.21456.
  5. Nurcahyo RA. Study Bax Expression Differences between ovarian endometriosis (endometrioma) and ovarian carcinoma serosum Differentiation Good. 2010.
  6. Eternal KC. Overview endometriosis in hospital pathology laboratory Dr. M. Djamil Padang period 2010-2013. 2014 Nov 18 [cited 2019 Sep 5]
  7. UC Ju, Dae W, K Seok, Kim M. The effect of concurrent endometriosis on the prognosis of women with ovarian endometrioid or clear cell carcinoma. Int J Gynecol Obstet. 2019;146: 177–183. DOI: 10.1002/ijgo.12861
  8. Parasar P, Ozcan P, Terry KL. Endometriosis: Epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 2017; 6 (1): 34-41. DOI: 10.1007/s13669-017-0187-1
  9. Rambe IR, Asri A. Ovarian malignant tumors profile in laboratory of pathology, Faculty of Medicine, University of Andalas period January 2011 until December 2012. J Kesehat Andalas. 2014;3(1): 54-7. DOI:
  10. BL years, Arania R, Windarti I. Characteristics of ovarian cancer patients at the Dr. H. Abdul Moeloek Hospital Bandar Lampung 2009-2013 Period. Juke Unila. 2015; 2-6.
  11. Momenimovahed Z, Tiznobaik A, Taheri S, Salehiniya H. Ovarian cancer in the world: Epidemiology and risk factors. Int J Womens Health. 2019;11:287-99.
  12. Wei JJ, William J, Bulun S. Endometriosis and ovarian cancer: a review of clinical, pathologic, and molecular aspects. Int J Gynecol Pathol. 2011;30(6):553-68. DOI:10.1097/PGP.0b013e31821f4b85.
  13. Králíčková M, Vetvicka V. Endometriosis and ovarian cancer. World J Clin Oncol. 2014;5(5):800. DOI: 10.5306/wjco.v5.i5.800

How to Cite

Muhammad, S., & Ghina Muthmainnah A Yasin. (2022). Relations between the incidence of endometriosis and type 1 epithelial ovarian cancer at M Djamil Central Hospital of Padang Indonesia. Bali Medical Journal, 12(1), 119–122.




Search Panel