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Correlation of chest radiography of confirmed COVID-19 patients with comorbid hypertension and diabetes mellitus

  • Ana Majdawati ,
  • Annisa ,

Abstract

Introduction: Several studies showed 324 severe cases of COVID-19 and 1234 mild cases with the highest comorbidities of Hypertension, Diabetes Mellitus, Chronic Obstruvtives Pulmonary Disease (COPD), and Cardiovascular disease. These comorbid factors lead to a poor prognosis in COVID-19. Chest radiography is an important modality as one of the parameters that can indicate the severity of COVID-19. This study aims to determine the relationship between Covid-19, comorbid Hypertension, and Diabetes Mellitus with chest radiography.

Method: This research is analitic observational with cross-sectional, relationship between Covid-19 patients with comorbid Hypertension and Diabetes Mellitus with chest radiography (type, location, and extent of lesions) that Modified Chest X-Ray Scoring System in Evaluating Severity of COVID-19 Patient in Dr. Soetomo General Hospital Surabaya, Indonesia in 2021, COVID-19 radiology category.  The data from PKU Muhammadiyah Gamping Hospital, Yogyakarta retrospectively from the medical records of Covid-19 patients who met the inclusion and exclusion criteria. Chi-Square analyzed the results variables with unpaired categorization.

Result: Most of the respondents who had comorbid diseases had moderate chest radiological features (65.4%) and those who did not have comorbid diseases had mild chest radiological features (71.9%), the results of chi-square data analysis between variables were p: 0.000.

Conclusion: The results of data analysis showed that comorbid diseases had a significant relationship with chest radiography in patients with confirmed COVID-19. The novelty of this study is the importance of radiological modalities as one of the parameters that can indicate the severity of Covid-19 patients with comorbidities.

References

  1. Ceraolo C, Giorgi FM. Genomic variance of the 2019-nCoV coronavirus. J Med Virol. 2020;92(5):522–8.
  2. Djalante R, Lassa J, Setiamarga D, Sudjatma A, Indrawan M. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID- 19 . The COVID-19 resource centre is hosted on Elsevier Connect , the company ’ s public news and information. Prog Disaster 6 100091. 2020;6(April):1–9.
  3. Guan WJ, Liang WH, He JX, Zhong NS. Cardiovascular comorbidity and its impact on patients with COVID-19. Eur Respir J. 2020;55(6):1069–76.
  4. Liu H, Chen S, Liu M, Nie H, Lu H. Comorbid chronic diseases are strongly correlated with disease severity among COVID-19 patients: A systematic review and meta-analysis. Aging Dis. 2020;11(3):668–78.
  5. Cheng S, Zhao Y, Wang F, Chen Y, Kaminga AC, Xu H. Comorbidities’ potential impacts on severe and non-severe patients with COVID-19: A systematic review and meta-analysis. Medicine (Baltimore). 2021;100(12):e24971.
  6. Kementerian Kesehatan RI. Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MenKes/413/2020 Tentang Pedoman Pencegahan dan Pengendalian Coronavirus Disease 2019 (Covid-19. MenKes/413/2020. 2020;2019:1–207.
  7. A. B, X. M, M. H, Y. Y, Z.A. F, N. Z, et al. Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology. 2020;295(3):200463.
  8. Parry AH, Wani AH, Yaseen M, Dar KA, Choh NA, Khan NA, et al. Spectrum of chest computed tomographic (CT) findings in coronavirus disease-19 (COVID-19) patients in India. Eur J Radiol. 2020;129(June):109147.
  9. Surendra H, Elyazar IR, Djaafara BA, Ekawati LL, Saraswati K, Adrian V, et al. Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study. Lancet Reg Heal - West Pacific. 2021;9:100108.
  10. Biswas M, Rahaman S, Biswas TK, Haque Z, Ibrahim B. Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Intervirology. 2021;64(1):36–47.
  11. Patanavanich R, Glantz SA. Smoking is associated with worse outcomes of COVID-19 particularly among younger adults: a systematic review and meta-analysis. BMC Public Health. 2021;21(1):1–9.
  12. He Y, Sun J, Ding X, Wang Q. Mechanisms in which smoking increases the risk of covid-19 infection: A narrative review. Iran J Public Health. 2021;50(3):431–7.
  13. Chen Q, Zheng Z, Zhang C, Zhang X, Wu H, Wang J, et al. Clinical characteristics of 145 patients with corona virus disease 2019 (COVID-19) in Taizhou, Zhejiang, China. Infection. 2020;48(4):543–51.
  14. Zumla A, Hui DS, Azhar EI, Memish ZA, Maeurer M. Reducing mortality from 2019-nCoV: host-directed therapies should be an option. Lancet. 2020;395(10224):e35–6.
  15. Setiawati R, Widyoningroem A, Handarini T, Hayati F, Basja AT, Surya ARD, et al. Modified chest X-ray scoring system in evaluating severity of COVID-19 patient in dr. Soetomo general hospital Surabaya, Indonesia. Int J Gen Med. 2021;14:2407–12.
  16. G. Targhera,*, A. Mantovania, X.-B. Wangb, H.-D. Yanc, Q.-F. Sund, K.-H. Pane, C.D. Byrnef, K.I. Zhengg, Y.-P. Cheng, h, M. Eslami, J. Georgei M-HZ. Patients with Diabetes are at higher risk for severe illness from COVID-19. Res Lett / Diabetes Metab. 2020;46(May):335–42.
  17. Fadini GP, Morieri ML, Longato E, Bonora BM, Pinelli S, Selmin E, et al. Exposure to dipeptidyl-peptidase-4 inhibitors and COVID-19 among people with type 2 diabetes: A case-control study. Diabetes, Obes Metab. 2020;22(10):1946–50.
  18. Wang C, Xie J, Zhao L, Fei X, Zhang H, Tan Y, et al. Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients. EBioMedicine. 2020;57:102833.
  19. Moon SJ, Rhee EJ, Lee WY, Yoon KH. Independent impact of diabetes on the severity of coronavirus disease 2019 in 5,307 patients in South Korea: A nationwide cohort study (Diabetes Metab J 2020;44:737-46). Diabetes Metab J. 2020;44(6):942–3.
  20. Zekavat SM, Honigberg M, Pirruccello JP, Kohli P, Karlson EW, Newton-Cheh C, et al. Elevated Blood Pressure Increases Pneumonia Risk: Epidemiological Association and Mendelian Randomization in the UK Biobank. Med. 2021;2(2):137-148.e4.
  21. Khan A, Benthin C, Zeno B, Albertson TE, Boyd J, Christie JD, et al. A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome. Crit Care. 2017;21(1):1–9.
  22. Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19. N Engl J Med. 2020;382(17):1653–9.
  23. Liang J, Jin G, Liu T, Wen J, Li G, Chen L, et al. Clinical characteristics and risk factors for mortality in cancer patients with COVID-19. Front Med. 2021;15(2):264–74.
  24. Wenham C, Smith J, Morgan R. COVID-19: the gendered impacts of the outbreak. Lancet. 2020;395(10227):846–8.
  25. Kaufman AE, Naidu S, Ramachandran S, Kaufman DS, Fayad ZA, Mani V. Review of radiographic findings in COVID-19. World J Radiol. 2020;12(8):142–55.
  26. Ng MY, Lee EYP, Yang J, Yang F, Li X, Wang H, et al. Imaging profile of the covid-19 infection: Radiologic findings and literature review. Radiol Cardiothorac Imaging. 2020;2(1).
  27. Novelli F, Pinelli V, Chiaffi L, Carletti AM, Sivori M, Giannoni U, et al. Prognostic significance of peripheral consolidations at chest x-ray in severe COVID-19 pneumonia. Radiol Med. 2022;127(6):602–8.

How to Cite

Majdawati, A., & Annisa. (2022). Correlation of chest radiography of confirmed COVID-19 patients with comorbid hypertension and diabetes mellitus. Bali Medical Journal, 11(3), 1644–1648. https://doi.org/10.15562/bmj.v11i3.3691

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