Comparison of the nutritional status and lipid profile of tuberculosis patients with and without type 2 diabetes mellitus in primary health care in Bandung

Afiat Berbudi , Chansa Camilla, Nofri Rahmadika, Adi Imam Cahyadi, Rovina Ruslami

Afiat Berbudi
Department of Biomedical Sciences, Parasitology Division, Faculty of Medicine Universitas Padjadjaran, Bandung, Indonesia. Email: a.berbudi@unpad.ac.id

Chansa Camilla
Undergraduate program of Faculty of Medicine, Universitas Padjadjaran

Nofri Rahmadika
Infectious Disease Research Center, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia

Adi Imam Cahyadi
Department of Biomedical Sciences, Microbiology Division, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia

Rovina Ruslami
Department of Biomedical Sciences, Pharmacology and Therapy Division, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
Online First: August 31, 2021 | Cite this Article
Berbudi, A., Camilla, C., Rahmadika, N., Cahyadi, A., Ruslami, R. 2021. Comparison of the nutritional status and lipid profile of tuberculosis patients with and without type 2 diabetes mellitus in primary health care in Bandung. Bali Medical Journal 10(2): 910-914. DOI:10.15562/bmj.v10i2.2474

Background: Diabetes mellitus (DM) and tuberculosis (TB) both are major global health problems. DM, primarily type 2 DM (T2DM) is often associated with obesity, hypertriglyceridemia, and high cholesterol and is a risk factor for TB. Diabetes is also associated with poor TB treatment outcomes. Since Mycobacterium tuberculosis (Mtb) relies on host nutrients, lipids, and cholesterol to survive, more knowledge about the nutritional status and lipid profile of T2DM, TB, and TB-T2DM patients is needed in order to establish novel TB management strategies for TB-T2DM patients.

Methods: Cross-sectional study was conducted to compare the nutritional status and lipid profile of TB-T2DM, TB, and T2DM only patients using data collected from several Primary Health Cares in Bandung, Indonesia. In total, 77 TB-T2DM, TB only, and T2DM only patients treated at the Primary Health Care Centers in Bandung, Indonesia, were recruited.

Results: BMI and the lipid profiles of the TB patients were significantly lower than those of T2DM patients (p<0.05). BMI and HDL levels were significantly lower in the TB-T2DM patients than those in T2DM patients (p<0.001 and p=0.04). Total cholesterol levels were significantly lower in TB compared to those in the TB-T2DM group (p=0.025).

Conclusion: All lipid profiles showed a similar pattern with the T2DM without TB having the highest lipid levels, followed by TB-T2DM and TB patients. 


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