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The potential of sunscreen preparation containing ethanol extract of Moringa oliefera leaves in nanoemulgel formulation



Abstract

Introduction: Quercetin (3, 3'4', 5.7-pentahydroxyflavone) within Moringa oliefera leaves is known to prevent cellular damage and dermal inflammation due to ultraviolet light exposure. However, its administration in Nanoemulgel form, which gives the cosmetics a good stability and compound release, is not yet evaluated. Therefore, this study aimed to characterize and develop a nanoemulgel sunscreen preparation containing Moringa oliefera leaves.

Methods: Design and optimization using simplex lattice design were performed. The optimum formulation for three independent variables involved propylene glycol- (X3), tween 20- (X2), and oleic acid oil- (X1) with a percentage ratio at 11.31; 77.50 and 11.19, respectively.

Results: The results showed that the optimum nanoemulgel formulation yielded an SPF value at 33.35, with a percentage of transmittance at 88.03. The emulsification time was recorded at 19.19s with droplet diameter at 138.0-nm with zeta potential at -37.1mV and polydispersity index at 0.537.

Conclusion: This study concluded that the moringa leaf nanoemulgel sunscreen was successfully formulated with a high SPF value.

Keywords: Quercetin Nanoemulgel nanoemulsion Moringa oleifera leaves

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How to Cite

Indrayani, A. W., Artini, I. G. A., Widhiarthini, I. A. A., Tianing, N. W., & Jawi, I. M. (2020). The potential of sunscreen preparation containing ethanol extract of Moringa oliefera leaves in nanoemulgel formulation. Bali Medical Journal, 9(3), 893–903. https://doi.org/10.15562/bmj.v9i3.2081
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Agung Wiwiek Indrayani
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I Gusti Ayu Artini
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Ida Ayu Alit Widhiarthini
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Ni Wayan Tianing
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I Made Jawi
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