Background: Prostate Specific Antigen (PSA) is one of the most important biomarkers in the diagnosis, follow-up, and determining the prognosis of prostate cancer. PSA examination can be used to detect the progress of prostate cancer earlier. This research aimed to determine the distribution of PSA levels in male adults in Yogyakarta based on their age groups.
Methods: This study was a descriptive study. Data were taken from the medical records of Medical Check-Up (MCU) patients with no symptoms of prostate abnormality. The research subject was limited to adult men who undertook MCU at JIH Hospital Yogyakarta, with a total of 250 participants fulfilling the inclusion and exclusion criteria. Data were taken from 2014 to 2018. Participantsâ€™ age was categorized into age groups. The mean, median, the lowest 95%, and the highest 95% were measured descriptively in each group.
Results: The mean serum PSA level was 1.42 Â± 1.31 ng/ml in the under 40-year-old group, 1.05 Â± 0.42 ng/ml in the 40-49-year-old group, 2.49 Â± 5.02 ng/ml in the 50-59-year-old group, 24.83 Â± 122.64 ng/ml in the 60-69-year-old group, 25.54 Â± 42.59 ng/ml in the 70-79-year-old group, and 7.66 Â± 6.72 ng/ml in the â‰¥ 80-year-old group. The level of PSA increased with age.
Conclusion: PSA levels in healthy adult men in Yogyakarta increased with age and PSA levels in Yogyakarta were higher than other populations across the world.